Mirtazapine is a type of antidepressant commonly marketed under the brand name Remeron. Mirtazapine helps to improve mood by restoring neurochemical balance in the brain. The side effects of mirtazapine can range from lightheadedness to constipation and even thoughts of suicide. With this side effect present in approximately two percent of children, the U.S. Food and Drug Administration has yet to approve it for use by children.
According to the Mayo Clinic, mirtazapine is from a class of drugs known as tetracyclic antidepressants. Mirtazapine can be used in the treatment of depression, post-traumatic stress disorder, and insomnia among other conditions. It is available in two tablet forms, a standard pill taken with water and a dissolving version that melts on the tongue. The medication is typically taken once daily around bedtime, however the prescribed dosage is higher for some patients. Various side effects of mirtazapine can develop, including an exacerbation of the existing depression.
One of the most problematic possible side effects of mirtazapine is worsening of existing depression symptoms, often accompanied by thoughts of suicide. Though this develops in only a small percentage of users, it is most prominent in younger individuals. As a result, it is not FDA approved for children under 18, though it is still sometimes prescribed to minors. Young people who are given mirtazapine should be monitored during the early days of use; if depression worsens or thoughts of suicide develop, it should be immediately brought to the attention of the doctor.
The National Institutes of Health report several other possible side effects of mirtazapine or Remeron. These include lightheadedness, dizziness, and drowsiness. In addition, confusion, anxiousness, and strange dreams may develop. Other common side effects of mirtazapine include dry mouth, nausea and vomiting, and constipation. The Mayo Clinic also reports that side effects of mirtazapine may include an increased appetite along with abnormal weight gain. Sometimes, side effects will occur for the first couple of weeks of use, but if they persist talk to your doctor.
Some side effects of mirtazapine can be serious and indicative of an allergic reaction. These side effects include skin rash or hives, swelling, difficulty breathing, flu-like symptoms, and seizures. In the event of any of these complications, seek medical attention immediately. Certain substances can also have drug interactions with mirtazapine. According to the University of Maryland Medical Center, these include ephedra, melatonin, psyllium, and St. John’s Wort, among others.
Mirtazapine, also known as Remeron, is an drug primarily used in treating depression and other similar conditions. The side effects of mirtazapine can include drowsiness, constipation, and nausea, and in some cases it can actually worsen depression. Talk to your doctor about any side effects of mirtazapine, particularly if they are severe, persistent, or include thoughts of suicide.
References:
Interactions with Mirtazapine. University of Maryland Medical Center.
Mirtazapine (marketed as Remeron) Information. U.S. Food and Drug Administration.
Mirtazapine. National Institutes of Health.
Mirtazapine (Oral Route). Mayo Clinic.
